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Z Shariat-Madar Selected Research

PF 04886847

6/2012PF-04886847 (an inhibitor of plasma kallikrein) attenuates inflammatory mediators and activation of blood coagulation in rat model of lipopolysaccharide (LPS)-induced sepsis.
4/2011Biochemical characterization of a novel high-affinity and specific plasma kallikrein inhibitor.

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Z Shariat-Madar Research Topics

Disease

2Thrombosis (Thrombus)
06/2012 - 01/2012
2Inflammation (Inflammations)
06/2012 - 04/2011
2Sepsis (Septicemia)
06/2012 - 02/2008
1Shock
06/2012
1Disseminated Intravascular Coagulation
06/2012
1Hemorrhage
06/2012
1Carotid Artery Thrombosis
01/2012
1Cardiovascular Diseases (Cardiovascular Disease)
04/2011
1Body Weight (Weight, Body)
04/2010
1Obesity
04/2010
1Weight Loss (Weight Reduction)
04/2010
1Hereditary Angioedemas
07/2009
1Edema (Dropsy)
07/2009
1Pain (Aches)
07/2009
1Tonsillitis
03/2009
1Rheumatoid Arthritis
03/2009
1Pre-Eclampsia (Preeclampsia)
03/2009
1Bacteremia
02/2008
1Septic Shock (Toxic Shock Syndrome)
02/2008

Drug/Important Bio-Agent (IBA)

2LipopolysaccharidesIBA
06/2012 - 04/2011
2Plasma KallikreinIBA
06/2012 - 02/2008
2PF 04886847IBA
06/2012 - 04/2011
2lysosomal Pro-X carboxypeptidaseIBA
01/2012 - 04/2010
2EnzymesIBA
04/2010 - 03/2009
1Dacarbazine (DIC)FDA LinkGeneric
06/2012
1EndotoxinsIBA
06/2012
1Enzyme Precursors (Zymogens)IBA
06/2012
1PrekallikreinIBA
06/2012
1N- dodecyl- 1- (pyrrolidine- 2- carbonyl)pyrrolidine- 2- carboxamideIBA
01/2012
1Kallikreins (Kallikrein)IBA
04/2011
1alpha-MSHIBA
04/2010
1peptide AIBA
07/2009
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
07/2009
1Blood Proteins (Serum Proteins)IBA
07/2009
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
07/2009
1Vasodilator Agents (Vasodilators)IBA
07/2009
1KininsIBA
02/2008
1Heparin (Liquaemin)FDA LinkGeneric
02/2008

Therapy/Procedure

1Drug Therapy (Chemotherapy)
04/2010